Aarhus University Seal / Aarhus Universitets segl

Applied cell biology and health biomarkers

Our research aim and focus

To identify and analyse health biomarkers in biological fluids and the developing fetus, and to conduct basic and applied cell research on bioactive and dietary components and their mechanism of action.

Our primary focus areas

  • Development and use of cell-based models (e.g. mammary gland and digestive tract) in relation to basic understanding of health and disease in animals and humans.
  • Identification and analyses of biomarkers and metabolites (e.g. short chain fatty acids, vitamins, anti-oxidants, cytokines, phenolic compounds, hormones and growth factors) in biological fluids, tissue homogenates and cells to understand health and to prevent diseases.
  • Effect and mechanism of action of bioactive and dietary components and metabolites in specific tissues by applied technologies (e.g. real time cell analyses and intracellular signaling).
  • Establishment of robust animal based cell models for in vitro milk production as an alternative solution for sustainable milk production.
  • Quality biomarkers of developing gametes (e.g. oocyte morphology and fertilization competence) and fetuses (e.g. developmental patterns) in relation to a healthy offspring.
  • Biodiversity biobanking (e.g. establishment of cell lines) as a conservation tool for threatened animal species.

Theme group coordinator

Stig Purup

Seniorforsker Institut for Husdyrvidenskab - ANIS Health

Our research perspectives

The research will contribute to:

  • a better understanding of health and prevention of diseases in animals and humans at both animal and cellular level
  • identify developmental factors that are important for the birth of a robust offspring
  • improve conservation of animal genetic diversity

The use of cell-based studies and biomarkers in specific tissues also represent possible research alternatives to animal models.